Our team will present several fertility research abstracts at ASRM 2022 in October
Patients know The Fertility Center of Las Vegas (FCLV) is an Oasis of Hope for anyone who wants to have a healthy baby. However, our Las Vegas fertility experts do more than provide exceptional fertility care. Our team also performs research that changes the practice of reproductive medicine. We’re excited to announce we will be presenting three fertility research abstracts at ASRM 2022 this October.
Showcasing one piece of research at this prestigious conference is a huge honor. The fact that our team will be presenting three research abstracts as e-posters is incredible. It shows FCLV’s commitment to research and allows us to improve fertility care for patients everywhere.
A look at the three fertility research abstracts that will be at ASRM 2022
The American Society for Reproductive Medicine (ASRM) hosts a conference every year in October. It’s a time for the brightest minds in reproductive medicine to share their knowledge, research and best practices.
Because our patients won’t be at ASRM 2022, our Las Vegas fertility experts are summarizing the research they’ll be presenting there.
THE EFFECT OF THE DAY OF BLASTOCYST FORMATION ON ONGOING PREGNANCY RATES IN PATIENTS RANDOMIZED TO FRESH OR FREEZE-ALL
Some embryos reach the blastocyst stage on Day 5, while others reach it on Day 6 after fertilization. The goal of this research was to compare fresh and frozen pregnancy rates among Day 5 and Day 6 blastocysts. To do this, our team looked at 204 embryo transfers.
Among fresh transfers, the ongoing pregnancy rate was significantly higher with Day 5 transfer than with Day 6 transfer (64.2% vs 37.5%). As a result, we concluded the day of blastocyst formation affects the outcomes of fresh transfers more than thawed embryo transfers.
We believe this is because fertility medications for ovarian stimulation can interfere with the development of the uterine lining. As such, slower blastocysts are less likely to implant if transferred in fresh cycles.
GESTATIONAL SAC DIAMETER IN EARLY PREGNANCY PREDICTS BIRTHWEIGHT AND PREMATURITY
With this research, we wanted to find out if information from ultrasounds during early pregnancy can help predict birthweight and prematurity. To accomplish this, we looked at 250 ultrasounds at 6.5 to 7 weeks gestation and 238 ultrasounds at 10 weeks.
- For the 6.5- to 7-week ultrasounds, the infant’s gender and gestational sac diameter could predict the infant’s birthweight.
- For the 10-week ultrasounds, the blastocyst expansion grade and the crown-rump length as well as the infant’s gender and gestational sac diameter could predict birthweight.
In all cases, a larger sac was associated with greater birthweight. Also, a smaller gestational sac size was associated with an increased risk of prematurity in the 6.5- to 7-week ultrasounds. However, this was not true in the 10-week ultrasounds.
BLASTOCYST PLOIDY IS NOT CORRELATED WITH THE CHOICE OF OVULATORY TRIGGER AGENT AFTER CONTROLLING FOR AGE AND COHORT SIZE
After ovarian stimulation to obtain multiple eggs for IVF, we must administer a “trigger” to mature the eggs before we can retrieve and fertilize them. This made our team wonder if the various “trigger” agents could result in different embryo quality.
In this research, we looked at 1,411 biopsied blastocysts (embryos) in the 2.5-year study period. Our team developed a model to predict preimplantation genetic testing for aneuploidy (PGT-A) test results. We found several significant predictors of abnormal PGT-A results.
- Increased patient age at retrieval
- Poorer trophectoderm (outer layer of the embryo) quality
- Delayed blastulation
- Fewer eggs collected
The trigger agent did not seem to influence whether an embryo was normal or abnormal. This suggests we can adjust the trigger for safety reasons without increasing the risk of having abnormal embryos.
You can visit a doctor that works at a renowned fertility clinic
Having our fertility research accepted for presentation at ASRM 2022 makes us very proud. Something else we’re proud of is our success rates. Our pregnancy rates are consistently among the highest in the United States, and we know these success rates translate to healthy babies.
If you’d like to meet with one of our Las Vegas fertility experts, contact us to schedule an appointment. We are here to help make your family-building dreams come true.